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No Pain, No Gain? How Much Should You Listen to Your Body?

The age old adage "No pain... no gain" officially went under the metaphorical microscope in a new study. Three different compounds, and only seen together rather than separately -- lactate, certain acids and ATP -- were found to be the catalyst for inducing a sense of fatigue. With increasing amounts of these three compounds, fatigue would continue to elevate due to the activation of a different set of neurons pertaining to pain. Under sufficient fatigue and neurons, the pain would signal to the body to quit to prevent muscle damage. While these may be fine for the average weekend warrior, professional athletes need to effectively manage this pain to continue setting new limits and goals. 

An extensive recap of the study can be seen over at the NY Times as they highlight in greater detail the testing protocol. 


  • Eugene Kan
  • AnatomyATPLactatePainScience

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